Description

2-Methanesulfonylpyridine-3-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because its unique structure, featuring both a carboxylic acid and a methanesulfonyl group on a pyridine ring, makes it a versatile intermediate for constructing complex molecules with tailored properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, drug discovery, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to introduce specific functional groups and modulate compound properties.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the development of specialty polymers and advanced materials.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	2-Methanesulfonylpyridine-3-Carboxylic Acid
CAS No.	442124-92-7
Molecular Formula	C7H7NO4S
Molecular Weight	201.20 g/mol
Synonyms	3-Pyridinecarboxylic acid, 2-(methylsulfonyl)-; 2-(Methylsulfonyl)nicotinic acid; 2-Methanesulfonylnicotinic acid; 2-(Methanesulfonyl)pyridine-3-carboxylic acid; 2-Mesylnicotinic acid; 2-Mesylpyridine-3-carboxylic acid; 2-Methylsulfonylpyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Methanesulfonylpyridine-3-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.