Description

1-[[[(1,1-Dimethylethyl)Diphenylsilyl]Oxy]Methyl]-Cyclopropanol is a high-value, organosilicon-protected cyclopropanol derivative, serving as a critical synthetic intermediate in advanced organic synthesis. Its core value lies in providing a masked hydroxyl functionality and a strained cyclopropane ring, enabling complex molecular construction with precise stereochemical control. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require sophisticated building blocks for drug discovery and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing cyclopropane motifs or requiring protected alcohol groups for selective reactions.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the cyclopropane structure can impart unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of novel monomers or functionalized polymers with specific thermal or mechanical properties.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry, including ring-opening reactions and cross-coupling protocols.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex fragrance, flavor, or electronic chemical compounds.

Basic Information

Product Name	1-[[[(1,1-Dimethylethyl)Diphenylsilyl]Oxy]Methyl]-Cyclopropanol
CAS No.	441784-82-3
Molecular Formula	C21H28O2Si
Molecular Weight	340.53 g/mol
Synonyms	1-(((tert-Butyldiphenylsilyl)oxy)methyl)cyclopropanol; 1-[[(tert-Butyldiphenylsilyl)oxy]methyl]cyclopropanol; (1-(tert-Butyldiphenylsilyloxymethyl)cyclopropanol; Cyclopropanol, 1-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-; TBDPS-protected cyclopropanol; tert-Butyldiphenylsilyl (cyclopropylhydroxymethyl) ether; 1-(TBDPSOCH2)cyclopropanol
EINECS	Contact for details

Quality Control

Our 1-[[[(1,1-Dimethylethyl)Diphenylsilyl]Oxy]Methyl]-Cyclopropanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to quality ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.