Description

2-Piperidinethione, 1-Ethyl-4-(Nitromethyl)- is a specialized heterocyclic organic compound featuring a piperidine core functionalized with a thione and a nitromethyl group. This unique molecular structure makes it a valuable and versatile building block in advanced organic synthesis, particularly for the development of novel pharmacologically active molecules. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating new chemical entities and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Synthesis Building Block: Serves as a versatile synthon for constructing complex nitrogen- and sulfur-containing heterocycles in medicinal chemistry.
• Ligand and Catalyst Development: Potential use in the preparation of specialized ligands for metal catalysis due to the thione and amine functionalities.
• Material Science Research: Investigated as a monomer or additive in the synthesis of specialized polymers with unique properties.

Basic Information

Product Name	2-Piperidinethione, 1-Ethyl-4-(Nitromethyl)-
CAS No.	441747-02-0
Molecular Formula	C8H14N2O2S
Molecular Weight	202.27 g/mol
Synonyms	1-Ethyl-4-(nitromethyl)piperidine-2-thione; 4-(Nitromethyl)-1-ethyl-2-piperidinethione; 1-Ethyl-4-nitromethyl-2-thioxopiperidine; 2-Thioxo-1-ethyl-4-nitromethylpiperidine; 2-Piperidinethione, 1-ethyl-4-(nitromethyl)-; 441747-02-0; 1-Ethyl-4-(nitromethyl)-2-piperidinethione
EINECS	Contact for details

Quality Control

Our 2-Piperidinethione, 1-Ethyl-4-(Nitromethyl)- is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our commitment to cGMP principles ensures reliable quality for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to the nitromethyl group, it should be handled as a potential oxidizer and stored separately from reducing agents and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.