Description

3-Amino-n-(3-Methylphenyl)-6,7-Dihydro-5H-Cyclopenta[B]Thieno[3,2-E]Pyridine-2-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for complex small molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex fused-ring systems containing thienopyridine and cyclopentane motifs.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to develop new therapeutic agents with optimized potency and selectivity.
• Process Chemistry Development: Acts as a standard or starting material for scaling up and optimizing synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: Used as an analytical standard for quality control and method validation in pharmaceutical analysis (HPLC, LC-MS).

Basic Information

Product Name	3-Amino-n-(3-Methylphenyl)-6,7-Dihydro-5H-Cyclopenta[B]Thieno[3,2-E]Pyridine-2-Carboxamide
CAS No.	441718-27-0
Molecular Formula	C18H17N3OS
Molecular Weight	323.41 g/mol
Synonyms	3-Amino-N-(3-methylphenyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide; 3-Amino-N-m-tolyl-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide; 441718-27-0; 3-Amino-N-(3-methylphenyl)-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide; Thienopyridine carboxamide derivative; Cyclopentathienopyridine intermediate
EINECS	Contact for details

Quality Control

Our 3-Amino-n-(3-Methylphenyl)-6,7-Dihydro-5H-Cyclopenta[B]Thieno[3,2-E]Pyridine-2-Carboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.