Description

Pent-4-Enyl-6-o-T-Butyldiphenylsilyl-D-Glucopyranoside is a sophisticated, protected carbohydrate derivative primarily used as a key synthetic intermediate in advanced organic and medicinal chemistry. Its value lies in the strategic protection of the 6-hydroxyl group with a robust tert-butyldiphenylsilyl (TBDPS) group, enabling selective functionalization of other positions on the sugar ring for complex molecule assembly. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries engaged in the synthesis of glycosides, glycoconjugates, and other bioactive molecules. The CAS number for this compound is provided in the table below.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel glycosylated drugs, prodrugs, and targeted therapeutic agents.
• Glycoconjugate Synthesis: Used in the preparation of complex glycoconjugates for biological studies, vaccine development, and diagnostic tools.
• Oligosaccharide Assembly: Serves as a protected glycosyl donor or acceptor in the iterative synthesis of specific oligosaccharide sequences.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies by allowing precise modification of carbohydrate scaffolds.
• Agrochemical Development: Applied in the research and synthesis of novel, bioactive carbohydrate-based pesticides or plant growth regulators.
• Chemical Biology Probes: Facilitates the creation of labeled sugar analogs for investigating carbohydrate metabolism and protein-carbohydrate interactions.

Basic Information

Product Name	Pent-4-Enyl-6-o-T-Butyldiphenylsilyl-D-Glucopyranoside
CAS No.	441311-03-1
Molecular Formula	C27H38O6Si
Molecular Weight	486.68 g/mol
Synonyms	6-O-(tert-Butyldiphenylsilyl)-D-glucopyranose pent-4-enyl glycoside; 4-Pentenyl 6-O-tert-butyldiphenylsilyl-β-D-glucopyranoside; 4-Pentenyl 6-O-TBDPS-β-D-glucopyranoside; TBDPS-protected D-glucose pentenyl glycoside; Pent-4-en-1-yl 6-O-[(1,1-dimethylethyl)diplenylsilyl]-β-D-glucopyranoside; β-D-Glucopyranoside, pent-4-en-1-yl 6-O-[(1,1-dimethylethyl)diphenylsilyl]-
EINECS	Contact for details

Quality Control

Our Pent-4-Enyl-6-o-T-Butyldiphenylsilyl-D-Glucopyranoside is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the primary container to prevent degradation. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation [α]²⁰D	-20° to -30° (c=1 in CHCl₃)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.