Description

4-Bromo-3-Phenylpyridine is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for coupling reactions and functional group transformations.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, especially those targeting kinase inhibition and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the pyridine core's bioactivity.
• Material Science: Serves as a building block for creating organic ligands in catalysis, as well as for developing advanced organic electronic materials and liquid crystals.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to introduce the 3-phenylpyridine moiety.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	4-Bromo-3-Phenylpyridine
CAS No.	440112-20-9
Molecular Formula	C11H8BrN
Molecular Weight	234.09 g/mol
Synonyms	3-Phenyl-4-bromopyridine; 4-Bromo-3-phenyl-pyridine; Pyridine, 4-bromo-3-phenyl-; 4-Brom-3-phenylpyridin; 4-Bromo-3-phenylpyridine (9CI)
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Phenylpyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.