Description

Cyclopropanecarboxylic Acid, 2-(Hydroxymethyl)-1-Methyl-, Ethyl Ester is a specialized organic ester featuring a cyclopropane ring, a hydroxymethyl group, and an ethyl ester moiety, making it a versatile chiral building block for advanced synthesis. This compound is valued for its unique steric and electronic properties, which are critical for constructing complex molecular architectures in fine chemical and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and intermediate manufacturing.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in constructing constrained ring systems.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the cyclopropane structure imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks.
• Fine Chemical Production: Employed in the manufacture of flavors, fragrances, and other high-value specialty chemicals requiring precise stereochemistry.
• Academic & Industrial Research: A valuable tool for methodological studies in organic chemistry, including ring-opening and functionalization reactions.
• Material Science Precursor: Potential use in developing monomers for specialized polymers with unique thermal or mechanical properties.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-(Hydroxymethyl)-1-Methyl-, Ethyl Ester
CAS No.	439913-09-4
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	Ethyl 2-(Hydroxymethyl)-1-methylcyclopropanecarboxylate; 1-Methyl-2-(hydroxymethyl)cyclopropanecarboxylic Acid Ethyl Ester; Ethyl 1-Methyl-2-(hydroxymethyl)cyclopropanecarboxylate; 2-(Hydroxymethyl)-1-methylcyclopropanecarboxylic Acid Ethyl Ester; (1-Methyl-2-(hydroxymethyl)cyclopropyl)methyl Ethyl Carbonate (tautomer); Cyclopropanecarboxylic acid, 2-(hydroxymethyl)-1-methyl-, ethyl ester; A building block for CGRP receptor antagonists
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-(Hydroxymethyl)-1-Methyl-, Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. We support compliance with relevant guidelines for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.