Description

1-Acetoxy-3-(Acetoxymethoxy)Carbonyl-2,2,5,5-Tetramethylpyrrolidine is a specialized pyrrolidine derivative that serves as a key synthetic intermediate and spin-labeling reagent. This compound is valued for its role in the synthesis of complex molecules and as a nitroxide precursor for Electron Paramagnetic Resonance (EPR) spectroscopy studies. It is primarily required by research institutions, pharmaceutical developers, and specialty chemical manufacturers engaged in advanced organic synthesis and biophysical analysis.

Application

• Nitroxide Spin Label Synthesis: A crucial precursor for creating stable free radicals used as spin probes and spin traps in EPR spectroscopy for studying molecular dynamics and structure.
• Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs), particularly those requiring complex heterocyclic frameworks.
• Polymer Chemistry: Acts as a functional monomer or cross-linking agent in the synthesis of specialty polymers with tailored properties.
• Bioconjugation Reagent: Employed to attach spin labels or other functional groups to biomolecules like proteins and nucleic acids for analytical purposes.
• Material Science Research: Utilized in the development of advanced materials, including liquid crystals and organic semiconductors.
• Organic Synthesis Building Block: Serves as a protected or activated form of a carboxylic acid derivative for constructing complex molecular architectures.

Basic Information

Product Name	1-Acetoxy-3-(Acetoxymethoxy)Carbonyl-2,2,5,5-Tetramethylpyrrolidine
CAS No.	439858-40-9
Molecular Formula	C15H23NO7
Molecular Weight	329.35 g/mol
Synonyms	3-[(Acetoxymethoxy)carbonyl]-2,2,5,5-tetramethyl-1-pyrrolidinyl acetate; 1-Acetoxy-3-carboxymethoxycarbonyl-2,2,5,5-tetramethylpyrrolidine acetate ester; 3-(Acetoxymethoxycarbonyl)-2,2,5,5-tetramethylpyrrolidine-1-acetate; TEMPO acetate derivative; Pyrrolidine, 1-(acetyloxy)-3-[[(acetyloxy)methoxy]carbonyl]-2,2,5,5-tetramethyl-; Acetoxymethyl 2,2,5,5-tetramethyl-1-acetoxypyrrolidine-3-carboxylate; Nitroxide precursor CAS 439858-40-9
EINECS	Contact for details

Quality Control

Our 1-Acetoxy-3-(Acetoxymethoxy)Carbonyl-2,2,5,5-Tetramethylpyrrolidine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.