Description

Pentanoic Acid, 2,5-Difluoro-3-Oxo-, Methyl Ester is a high-purity fluorinated keto ester building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is a critical strategy for modulating biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, including protease inhibitors, kinase inhibitors, and novel herbicides.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), especially protease and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where fluorine substitution enhances efficacy and environmental profile.
• Advanced Material Precursor: Serves as a monomer or modifier in the synthesis of specialty polymers and materials with tailored properties.
• Organic Synthesis Reagent: Employed in academic and industrial research for constructing complex molecular architectures via reactions at the keto and ester functional groups.
• Fluorine Chemistry Research: A valuable substrate for studying novel fluorination reactions and developing new synthetic methodologies.

Basic Information

Product Name	Pentanoic Acid, 2,5-Difluoro-3-Oxo-, Methyl Ester
CAS No.	439809-76-4
Molecular Formula	C7H8F2O3
Molecular Weight	178.14 g/mol
Synonyms	Methyl 2,5-difluoro-3-oxopentanoate; 2,5-Difluoro-3-oxopentanoic acid methyl ester; 3-Oxopentanoic acid, 2,5-difluoro-, methyl ester; Methyl 3-oxo-2,5-difluoropentanoate; 2,5-Difluoro-3-oxovaleric acid methyl ester; Difluorinated keto ester; Fluorinated levulinate derivative
EINECS	Contact for details

Quality Control

Our Pentanoic Acid, 2,5-Difluoro-3-Oxo-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.