Description

Ethyl 4-Cyclopropyl-1,3-Thiazole-2-Carboxylate is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce the unique 4-cyclopropylthiazole moiety into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the cyclopropyl-thiazole core can contribute to novel modes of action.
• Material Science: Acts as a building block for advanced organic materials, such as ligands for catalysis or components in organic electronic devices.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects requiring this precise heterocyclic scaffold.

Basic Information

Product Name	Ethyl 4-Cyclopropyl-1,3-Thiazole-2-Carboxylate
CAS No.	439692-05-4
Molecular Formula	C9H11NO2S
Molecular Weight	197.25 g/mol
Synonyms	Ethyl 4-cyclopropyl-1,3-thiazole-2-carboxylate; 2-Carbethoxy-4-cyclopropylthiazole; 4-Cyclopropyl-1,3-thiazole-2-carboxylic acid ethyl ester; Ethyl 4-cyclopropylthiazole-2-carboxylate; 4-Cyclopropylthiazole-2-carboxylic acid ethyl ester; 2-Thiazolecarboxylic acid, 4-cyclopropyl-, ethyl ester; 439692-05-4
EINECS	Contact for details

Quality Control

Our Ethyl 4-Cyclopropyl-1,3-Thiazole-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.