Description

6-Chloro-4-Methoxypyridin-2-Amine is a high-purity, versatile pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core.
• Ligand and Catalyst Preparation: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	6-Chloro-4-Methoxypyridin-2-Amine
CAS No.	439146-20-0
Molecular Formula	C6H7ClN2O
Molecular Weight	158.59 g/mol
Synonyms	2-Amino-6-chloro-4-methoxypyridine; 4-Methoxy-6-chloropyridin-2-amine; 6-Chloro-4-methoxy-2-pyridinamine; 6-Chloro-4-methoxypyridin-2-ylamine; 2-Pyridinamine, 6-chloro-4-methoxy-; 439146-20-0; 6-Chloro-4-methoxy-2-aminopyridine
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-Methoxypyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.