Description

Imidazo[1,2-A]Pyridine-8-Carbonitrile, 1,2,3,5-Tetrahydro-5-Oxo- (9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure incorporating a nitrile and a ketone functional group. This compound is of significant value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Serves as a structural motif for developing new pesticides and herbicides with specific modes of action.
• Material Science: Used in the research and development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology: Employed as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Academic & Contract Research: Supplied to universities and CROs for fundamental research in heterocyclic chemistry and novel synthetic methodology development.

Basic Information

Product Name	Imidazo[1,2-A]Pyridine-8-Carbonitrile, 1,2,3,5-Tetrahydro-5-Oxo- (9Ci)
CAS No.	439118-89-5
Molecular Formula	C8H5N3O
Molecular Weight	159.15 g/mol
Synonyms	1,2,3,5-Tetrahydro-5-oxoimidazo[1,2-a]pyridine-8-carbonitrile; 8-Cyano-1,2,3,5-tetrahydro-5-oxoimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine-8-carbonitrile, 1,2,3,5-tetrahydro-5-oxo-; 439118-89-5; 5-Oxo-1,2,3,5-tetrahydroimidazo[1,2-a]pyridine-8-carbonitrile
EINECS	Contact for details

Quality Control

Our Imidazo[1,2-A]Pyridine-8-Carbonitrile, 1,2,3,5-Tetrahydro-5-Oxo- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.