Description

4-[4-(tert-Butyl)Benzoyl]-n-(3-Pyridinylmethyl)-1H-Pyrrole-2-Carboxamide is a high-purity, non-peptidic small molecule organic compound of significant interest in advanced pharmaceutical research and development. Its complex molecular architecture, featuring a pyrrole carboxamide core linked to a tert-butyl benzoyl moiety and a pyridinylmethyl group, makes it a valuable synthetic intermediate and a key scaffold for probing biological pathways. This compound is primarily utilized by research chemists and process development scientists in the life sciences sector. It serves as a critical building block for the synthesis of novel therapeutic agents and as a reference standard in analytical and pharmacological studies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Biochemical Research: Used as a reference standard or a probe molecule in enzymatic assays, receptor binding studies, and other in-vitro pharmacological evaluations.
• Chemical Biology: Acts as a scaffold for developing chemical tools to study protein-protein interactions and cellular signaling pathways.
• Process Chemistry Development: Employed in route scouting, optimization, and scale-up studies for the production of active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Provides a high-purity benchmark for method development and validation in quality control laboratories using HPLC, LC-MS, or NMR.
• Library Synthesis: Used to generate focused libraries of analogs for structure-activity relationship (SAR) studies to optimize potency and selectivity.

Basic Information

Product Name	4-[4-(tert-Butyl)Benzoyl]-n-(3-Pyridinylmethyl)-1H-Pyrrole-2-Carboxamide
CAS No.	439111-45-2
Molecular Formula	C22H25N3O2
Molecular Weight	363.46 g/mol
Synonyms	4-[4-(tert-Butyl)benzoyl]-N-(pyridin-3-ylmethyl)-1H-pyrrole-2-carboxamide; 1H-Pyrrole-2-carboxamide, 4-[4-(1,1-dimethylethyl)benzoyl]-N-3-pyridinylmethyl-; N-(3-Pyridinylmethyl)-4-[4-(1,1-dimethylethyl)benzoyl]-1H-pyrrole-2-carboxamide; 4-(4-tert-Butylbenzoyl)-N-(pyridin-3-ylmethyl)-1H-pyrrole-2-carboxamide; CAS 439111-45-2
EINECS	Contact for details

Quality Control

Our 4-[4-(tert-Butyl)Benzoyl]-n-(3-Pyridinylmethyl)-1H-Pyrrole-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.