Description

1,3-Dimethyl-4-Methoxypyrazolo[3,4-B]Pyridine-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This heterocyclic carboxylic acid derivative serves as a key building block for synthesizing novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in developing innovative small-molecule drugs, particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex pyrazolopyridine-based molecular scaffolds with specific biological activity.
• Research & Development (R&D): Essential for academic and industrial research labs exploring new chemical entities and structure-activity relationships (SAR).
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the commercial-scale production of approved pharmaceutical compounds requiring this specific heterocyclic core.
• Contract Manufacturing Organizations (CMOs): Supplied to CMOs and CDMOs producing custom synthesis batches for clinical trials and commercial supply.

Basic Information

Product Name	1,3-Dimethyl-4-Methoxypyrazolo[3,4-B]Pyridine-5-Carboxylic Acid
CAS No.	439109-76-9
Molecular Formula	C11H11N3O3
Molecular Weight	233.22 g/mol
Synonyms	4-Methoxy-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid; 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic acid, 4-methoxy-1,3-dimethyl-; 1,3-Dimethyl-4-methoxy-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid; Pyrazolo[3,4-b]pyridine-5-carboxylic acid, 1,3-dimethyl-4-methoxy-; CAS 439109-76-9
EINECS	Contact for details

Quality Control

Our production of 1,3-Dimethyl-4-Methoxypyrazolo[3,4-B]Pyridine-5-Carboxylic Acid adheres to stringent quality management systems, ensuring batch-to-batch consistency and high purity suitable for pharmaceutical applications. All material is characterized and released according to comprehensive in-house specifications, which typically include identity confirmation by spectroscopic methods (IR, NMR), purity assessment by HPLC, and control of specific impurities. A Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.