Description

3,4-Diamino-6-Trifluoromethylpyridine is a high-purity, multi-functional heterocyclic building block characterized by its unique trifluoromethyl and diamine substitution pattern. This compound is a critical intermediate for the synthesis of advanced pharmaceutical agents and agrochemicals, where its structure imparts desirable properties such as metabolic stability and enhanced bioavailability. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine core and fluorine atoms.
• Ligand and Catalyst Preparation: Serves as a precursor for nitrogen-donor ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the creation of organic electronic materials, such as charge-transport layers or fluorinated polymers.
• Chemical Biology Probes: Useful for developing fluorescent tags or molecular probes due to its derivatizable amino groups.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific, fluorinated pyridine scaffolds.

Basic Information

Product Name	3,4-Diamino-6-Trifluoromethylpyridine
CAS No.	438564-37-5
Molecular Formula	C6H6F3N3
Molecular Weight	177.13 g/mol
Synonyms	6-(Trifluoromethyl)pyridine-3,4-diamine; 3,4-Diamino-6-(trifluoromethyl)pyridine; 6-Trifluoromethyl-3,4-pyridinediamine; 3,4-Pyridinediamine, 6-(trifluoromethyl)-; 2-Amino-5-(trifluoromethyl)pyridine-4-amine; 4-Amino-6-(trifluoromethyl)pyridine-3-amine
EINECS	Contact for details

Quality Control

Our 3,4-Diamino-6-Trifluoromethylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.