Description

4-Chloro-5-Nitro-2-(Trifluoromethyl)Pyridine is a high-purity, multi-functional heterocyclic building block of significant commercial importance. Its unique structure, featuring chloro, nitro, and trifluoromethyl substituents on a pyridine core, makes it a versatile intermediate for synthesizing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, including herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for functional materials, such as liquid crystals, organic semiconductors, and specialty polymers.
• Chemical Biology & Proteomics: Employed as a reactive handle or linker in the synthesis of probes and tools for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to clients.
• Academic & Industrial R&D: Utilized in exploratory chemistry for discovering new reactions and building chemical libraries for screening.

Basic Information

Product Name	4-Chloro-5-Nitro-2-(Trifluoromethyl)Pyridine
CAS No.	438554-45-1
Molecular Formula	C6H2ClF3N2O2
Molecular Weight	226.54 g/mol
Synonyms	2-(Trifluoromethyl)-4-chloro-5-nitropyridine; 4-Chloro-5-nitro-2-(trifluoromethyl)pyridine; 4-Chloro-5-nitro-2-trifluoromethylpyridine; 2-Trifluoromethyl-4-chloro-5-nitropyridine; Pyridine, 4-chloro-5-nitro-2-(trifluoromethyl)-; 438554-45-1
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Nitro-2-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.