Description

2-(3-Bromo-1-(3-Chloropyridin-2-Yl)-1H-Pyrazol-5-Yl)-6-Chloro-3,8-Dimethylquinazolin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development pipelines targeting specific therapeutic areas. It is primarily required by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of investigational new drugs, particularly in medicinal chemistry programs.
• Agrochemical Research: Used in the development of next-generation crop protection agents and pesticides due to its complex pyrazole and quinazolinone motifs.
• Chemical Biology Probe: Serves as a core scaffold for creating molecular probes to study biological pathways and enzyme inhibition.
• Organic Synthesis Reference Standard: Employed as a high-purity standard for analytical method development and validation in QC laboratories.
• Material Science Research: Investigated for potential applications in creating novel organic electronic materials or metal-organic frameworks (MOFs).

Basic Information

Product Name	2-(3-Bromo-1-(3-Chloropyridin-2-Yl)-1H-Pyrazol-5-Yl)-6-Chloro-3,8-Dimethylquinazolin-4(3H)-One
CAS No.	438450-43-2
Molecular Formula	C₁₉H₁₂BrCl₂N₅O
Molecular Weight	477.14 g/mol
Synonyms	2-(3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl)-6-chloro-3,8-dimethyl-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 2-[3-bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethyl-; CAS 438450-43-2; 2-(3-Bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one; 6-Chloro-3,8-dimethyl-2-[3-bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl]-4(3H)-quinazolinone
EINECS	Contact for details

Quality Control

Our 2-(3-Bromo-1-(3-Chloropyridin-2-Yl)-1H-Pyrazol-5-Yl)-6-Chloro-3,8-Dimethylquinazolin-4(3H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the stringent requirements for advanced research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. This material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.