Description

Ethyl 3-Amino-6-(Difluoromethyl)-4-Methylthieno[2,3-B]Pyridine-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides, leveraging its difluoromethyl and thienopyridine motifs.
• Organic Synthesis Reagent: Used in academic and industrial R&D for constructing complex heterocyclic systems and exploring structure-activity relationships (SAR).
• Material Science Precursor: Potential application in the synthesis of organic electronic materials and specialty dyes due to its conjugated system.

Basic Information

Product Name	Ethyl 3-Amino-6-(Difluoromethyl)-4-Methylthieno[2,3-B]Pyridine-2-Carboxylate
CAS No.	438223-65-5
Molecular Formula	C13H12F2N2O2S
Molecular Weight	298.31 g/mol
Synonyms	Ethyl 3-Amino-6-(difluoromethyl)-4-methylthieno[2,3-b]pyridine-2-carboxylate; 3-Amino-6-(difluoromethyl)-4-methylthieno[2,3-b]pyridine-2-carboxylic acid ethyl ester; Thieno[2,3-b]pyridine-2-carboxylic acid, 3-amino-6-(difluoromethyl)-4-methyl-, ethyl ester; CAS 438223-65-5
EINECS	Contact for details

Quality Control

Our Ethyl 3-Amino-6-(Difluoromethyl)-4-Methylthieno[2,3-B]Pyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from strong alkalis and incompatible organic solvents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.