Description

4-(4-Chloro-Phenyl)-2-Thioxo-6-Trifluoromethyl-1,2-Dihydro-Pyridine-3-Carbonitrile is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters because it provides a versatile molecular scaffold containing reactive nitrile, thioxo, and trifluoromethyl groups, enabling the development of novel compounds with tailored properties. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients, as well as by fine chemical manufacturers producing specialty intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for therapeutic areas requiring fluorinated or sulfur-containing heterocycles.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the trifluoromethyl and chlorophenyl groups can contribute to biological activity and environmental stability.
• Material Science: Serves as a building block for advanced organic materials, such as ligands for catalysis or monomers for specialty polymers.
• Chemical Synthesis: Utilized in academic and industrial R&D for constructing complex pyridine and dihydropyridine derivatives via its reactive functional groups.
• Fluorine Chemistry: An important substrate for exploring structure-activity relationships (SAR) in medicinal chemistry due to the presence of the trifluoromethyl group.

Basic Information

Item	Details
Product Name	4-(4-Chloro-Phenyl)-2-Thioxo-6-Trifluoromethyl-1,2-Dihydro-Pyridine-3-Carbonitrile
CAS No.	438218-95-2
Molecular Formula	C13H6ClF3N2S
Molecular Weight	314.71 g/mol
Synonyms	4-(4-Chlorophenyl)-2-thioxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile; 2-Thioxo-4-(4-chlorophenyl)-6-(trifluoromethyl)-1,2-dihydro-3-pyridinecarbonitrile; 3-Cyano-4-(4-chlorophenyl)-6-(trifluoromethyl)-2(1H)-pyridinethione; 438218-95-2; 4-(p-Chlorophenyl)-2-mercapto-6-trifluoromethylnicotinonitrile
EINECS	Contact for details

Quality Control

Our 4-(4-Chloro-Phenyl)-2-Thioxo-6-Trifluoromethyl-1,2-Dihydro-Pyridine-3-Carbonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.