Description

4-Amino-3-Bromo-5-Iodo-Benzoic Acid Ethyl Ester is a high-purity, multi-halogenated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which provides multiple reactive sites for selective functionalization, enabling the construction of complex heterocyclic and pharmaceutical scaffolds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides with unique modes of action.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and material science.
• Functional Material Development: Employed in the research of organic semiconductors, liquid crystals, and advanced polymers.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis projects requiring halogen-diverse benzoic acid derivatives.

Basic Information

Product Name	4-Amino-3-Bromo-5-Iodo-Benzoic Acid Ethyl Ester
CAS No.	437707-51-2
Molecular Formula	C9H9BrINO2
Molecular Weight	369.99 g/mol
Synonyms	Ethyl 4-Amino-3-bromo-5-iodobenzoate; Benzoic acid, 4-amino-3-bromo-5-iodo-, ethyl ester; 3-Bromo-5-iodo-4-aminobenzoic acid ethyl ester; 4-Amino-3-bromo-5-iodobenzoic acid ethyl ester; AI3-52395; ZINC000103014757; AKOS005258169; BRN 14208951
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Bromo-5-Iodo-Benzoic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up processes with reliable, traceable material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.