Description

3-[(Pyridin-3-Ylmethyl)-Carbamoyl]-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid is a high-purity, synthetically valuable bicyclic compound featuring a norbornene core functionalized with a pyridinylmethyl carboxamide group. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex organic frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Building Block: Used in structure-activity relationship (SAR) studies and combinatorial chemistry libraries due to its rigid, three-dimensional norbornene scaffold.
• Agrochemical Research: Employed in the development of new pesticides and herbicides, leveraging its complex heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with specialized thermal or mechanical properties.
• Academic & Institutional Research: Used in universities and research institutes for fundamental studies in organic synthesis and chemical biology.

Basic Information

Product Name	3-[(Pyridin-3-Ylmethyl)-Carbamoyl]-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid
CAS No.	436811-05-1
Molecular Formula	C16H16N2O3
Molecular Weight	284.31 g/mol
Synonyms	3-[(3-Pyridylmethyl)carbamoyl]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid; 3-[(Pyridin-3-ylmethyl)carbamoyl]-2-norbornene-2-carboxylic acid; 5-Norbornene-2-carboxylic acid, 3-[(3-pyridinylmethyl)carbamoyl]-; Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-[(3-pyridinylmethyl)carbamoyl]-; 436811-05-1; N-(3-Pyridinylmethyl)-5-norbornene-2,3-dicarboximide precursor
EINECS	Contact for details

Quality Control

Our 3-[(Pyridin-3-Ylmethyl)-Carbamoyl]-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.