Description

4-(2,5-Dimethyl-Thiophen-3-Yl)-Thiazol-2-Ylamine is a high-purity, specialized heterocyclic organic compound featuring a thiophene-thiazole core structure. This molecule serves as a critical advanced pharmaceutical intermediate and a versatile building block in modern organic synthesis. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Serves as a core scaffold for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Building block for creating organic semiconductors, conductive polymers, and photoactive materials due to its electron-rich heterocyclic system.
• Chemical Biology & Proteomics: Used in the design and synthesis of molecular probes, enzyme inhibitors, and labeled compounds for biochemical research.
• Ligand & Catalyst Development: Employed in the preparation of novel ligands for transition metal catalysis and organocatalysts for asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	4-(2,5-Dimethyl-Thiophen-3-Yl)-Thiazol-2-Ylamine
CAS No.	436152-83-9
Molecular Formula	C9H10N2S2
Molecular Weight	210.32 g/mol
Synonyms	2-Amino-4-(2,5-dimethyl-3-thienyl)thiazole; 4-(2,5-Dimethyl-3-thienyl)-2-thiazolamine; 2-Thiazolamine, 4-(2,5-dimethyl-3-thienyl)-; 4-(2,5-Dimethylthiophen-3-yl)thiazol-2-amine; 4-(2,5-Dimethyl-3-thienyl)-2-aminothiazole; 4-(2,5-Dimethylthien-3-yl)thiazol-2-ylamine; 2-Amino-4-(2,5-dimethylthiophen-3-yl)thiazole
EINECS	Contact for details

Quality Control

Our production of 4-(2,5-Dimethyl-Thiophen-3-Yl)-Thiazol-2-Ylamine adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. The material is characterized and released using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We support compliance with cGMP and ISO 9001 standards for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.