Description

2-Pyridineethanamine, B,B-Difluoro-, Benzenesulfonate (1:1) is a high-purity, organofluorine building block and pharmaceutical intermediate. This compound is valued for its unique chemical structure, which incorporates a difluoroethylamine moiety linked to a pyridine ring, making it a versatile synthon for medicinal chemistry and advanced material synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine atoms to enhance bioavailability and metabolic stability.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry: An essential reagent for introducing the difluoroethylamine group into more complex molecular architectures in synthetic organic chemistry.
• Bioconjugation & Probe Development: Utilized in the design of biochemical probes and affinity labels for proteomics and diagnostic research.

Basic Information

Product Name	2-Pyridineethanamine, B,B-Difluoro-, Benzenesulfonate (1:1)
CAS No.	435345-04-3
Molecular Formula	C13H14F2N2O3S
Molecular Weight	316.32 g/mol
Synonyms	2-(2,2-Difluoroethylamino)pyridine benzenesulfonate; 2-[(2,2-Difluoroethyl)amino]pyridine benzenesulfonate salt; 2-Pyridin-2-ylethanamine, 2,2-difluoro-, benzenesulfonate; Benzenesulfonic acid compound with 2-[(2,2-difluoroethyl)amino]pyridine (1:1); 2-[(2,2-Difluoroethyl)amino]pyridine benzene sulfonate; 435345-04-3; 2-(2,2-Difluoroethylamino)pyridine benzene sulfonic acid salt
EINECS	Contact for details

Quality Control

Our 2-Pyridineethanamine, B,B-Difluoro-, Benzenesulfonate (1:1) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements for research and development. A detailed Certificate of Analysis (COA) with batch-specific data is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.