Description

1-(4-(2-Pyridyl)Piperazinyl)-2-(2-Thienyl)Ethan-1-One is a high-purity, advanced pharmaceutical intermediate featuring a distinct molecular architecture combining piperazine, pyridine, and thiophene moieties. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) and receptor-specific pathways. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in medicinal chemistry and preclinical development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic agents.
• Contract Manufacturing: Supplied to CDMOs for scale-up synthesis under current Good Manufacturing Practice (cGMP) conditions.
• Biochemical Research: Employed as a ligand or probe in biochemical assays to study receptor interactions and enzyme inhibition.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	1-(4-(2-Pyridyl)Piperazinyl)-2-(2-Thienyl)Ethan-1-One
CAS No.	433946-96-4
Molecular Formula	C15H17N3OS
Molecular Weight	287.38 g/mol
Synonyms	1-[4-(Pyridin-2-yl)piperazin-1-yl]-2-(thiophen-2-yl)ethan-1-one; 2-(2-Thienyl)-1-[4-(2-pyridinyl)-1-piperazinyl]ethanone; 1-(4-(2-Pyridinyl)-1-piperazinyl)-2-(2-thienyl)ethanone; 2-Thiopheneacetic acid, 4-(2-pyridinyl)-1-piperazinyl ester; Ethanone, 1-[4-(2-pyridinyl)-1-piperazinyl]-2-(2-thienyl)-
EINECS	Contact for details

Quality Control

Our 1-(4-(2-Pyridyl)Piperazinyl)-2-(2-Thienyl)Ethan-1-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.