Description

tert-Butyl 4-acetyl-2,2-dimethyloxazolidine-3-carboxylate is a high-value, protected amino acid derivative and a versatile chiral building block in advanced organic synthesis. Its primary value lies in its role as a key intermediate for constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-purity intermediates for asymmetric synthesis and peptide mimetics.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly in the development of protease inhibitors and other biologically active molecules.
• Peptidomimetics & Amino Acid Derivatives: Serves as a protected, functionalized amino acid scaffold for constructing non-natural peptides and peptide-like compounds with enhanced metabolic stability.
• Asymmetric Synthesis: Used as a chiral auxiliary or building block in stereoselective reactions to introduce controlled chirality into target molecules.
• Agrochemical Research: Employed in the discovery and development of new chiral active ingredients for crop protection agents.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic pathways in laboratory settings.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	tert-Butyl 4-Acetyl-2,2-Dimethyloxazolidine-3-Carboxylate
CAS No.	433683-01-3
Molecular Formula	C12H21NO4
Molecular Weight	243.30 g/mol
Synonyms	3-[(1,1-Dimethylethoxy)carbonyl]-4-acetyl-2,2-dimethyloxazolidine; tert-Butyl 4-acetyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate; Boc-4-Acetyl-2,2-dimethyloxazolidine; N-Boc-4-Acetyl-2,2-dimethyloxazolidine; 4-Acetyl-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester; (tert-Butoxycarbonyl)-4-acetyl-2,2-dimethyloxazolidine; Oxazolidine derivative CAS 433683-01-3
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-acetyl-2,2-dimethyloxazolidine-3-carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay purity, chiral purity (enantiomeric excess), and impurity profiles. While not a compendial item, production adheres to cGMP principles where applicable to support its use in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.