Description

4-Iodo-6-Methoxypyridin-3-Ol is a versatile halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both iodo and methoxy substituents, makes it a valuable intermediate for constructing complex molecules with high precision. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its halogenated pyridine core.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probes: Acts as a building block for creating molecular probes used to study biological pathways and enzyme functions.
• Advanced Material Development: Incorporated into the synthesis of organic electronic materials and liquid crystals due to its aromatic and modifiable structure.
• Cross-Coupling Reactions: Serves as a pivotal substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form complex biaryl systems.

Basic Information

Product Name	4-Iodo-6-Methoxypyridin-3-Ol
CAS No.	431942-27-7
Molecular Formula	C6H6INO2
Molecular Weight	250.02 g/mol
Synonyms	3-Hydroxy-4-iodo-6-methoxypyridine; 6-Methoxy-4-iodopyridin-3-ol; 4-Iodo-6-methoxy-3-pyridinol; 4-Iodo-6-methoxypyridin-3-ol; 431942-27-7; 3-Pyridinol, 4-iodo-6-methoxy-
EINECS	Contact for details

Quality Control

Our 4-Iodo-6-Methoxypyridin-3-Ol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) is supplied with each batch, detailing all specifications and test results. Our quality system is designed to meet the stringent requirements of research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.