Description

1-tert-Butyl 3-Methyl 2-Oxopyrrolidine-1,3-Dicarboxylate is a high-purity, protected pyrrolidinone derivative serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular scaffolds for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. Its primary value lies in enabling complex synthetic routes, particularly in medicinal chemistry for the creation of nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates, particularly those containing pyrrolidinone or proline-like structures.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing libraries of novel bioactive compounds in drug discovery programs.
• Peptidomimetic Development: Serves as a constrained, non-natural amino acid analog for designing enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Employed as an intermediate in the production of advanced pesticides and herbicides with specific chiral requirements.
• Material Science Precursor: Can be utilized in the synthesis of specialized polymers and functional materials requiring specific lactam-based monomers.

Basic Information

Product Name	1-tert-Butyl 3-Methyl 2-Oxopyrrolidine-1,3-Dicarboxylate
CAS No.	431079-79-7
Molecular Formula	C12H19NO5
Molecular Weight	257.28 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-3-methyl 3-carboxy-2-pyrrolidinone; 3-Methyl 1-tert-butyl 2-oxopyrrolidine-1,3-dicarboxylate; 1-Boc-3-methyl 3-carboxy-2-pyrrolidinone; tert-Butyl 3-(methoxycarbonyl)-2-oxo-1-pyrrolidinecarboxylate; 2-Oxopyrrolidine-1,3-dicarboxylic acid 1-tert-butyl 3-methyl ester; N-Boc-3-methoxycarbonyl-2-pyrrolidinone; 431079-79-7
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 3-Methyl 2-Oxopyrrolidine-1,3-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.