Description

Imidazo[1,2-A]Pyridine-5-Carboxaldehyde, 3-Bromo- is a high-value brominated heterocyclic building block, specifically an aldehyde-functionalized imidazopyridine derivative. This compound is critical for facilitating advanced molecular construction in pharmaceutical and agrochemical research, enabling the introduction of both aldehyde and bromo functional groups for further derivatization. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides by serving as a core scaffold for bioactive molecule design.
• Material Science: Employed in the creation of organic semiconductors, ligands for catalysis, and advanced polymers due to its electron-rich heterocyclic structure.
• Chemical Biology & Probe Development: Utilized as a versatile handle for bioconjugation and the creation of fluorescent probes or molecular tags.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Library Synthesis: A valuable building block for combinatorial and parallel synthesis in high-throughput screening libraries for drug discovery.

Basic Information

Product Name	Imidazo[1,2-A]Pyridine-5-Carboxaldehyde, 3-Bromo-
CAS No.	429690-43-7
Molecular Formula	C8H5BrN2O
Molecular Weight	225.04 g/mol
Synonyms	3-Bromoimidazo[1,2-a]pyridine-5-carboxaldehyde; 3-Bromo-5-formylimidazo[1,2-a]pyridine; 3-Bromoimidazo[1,2-a]pyridine-5-carbaldehyde; Imidazo[1,2-a]pyridine-5-carboxaldehyde, 3-bromo-; 429690-43-7; 3-Bromo-5-imidazo[1,2-a]pyridinecarboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of Imidazo[1,2-A]Pyridine-5-Carboxaldehyde, 3-Bromo- is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.