Description

(S)-Methyl-3-(1-Methyl-1H-Indol-3-Yl)-Phenyl-Propionate CAS NO 429689-17-8 is a high-purity chiral intermediate featuring a unique indole-phenyl propionate structure. This compound is critical for pharmaceutical research and development, particularly in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate its specific stereochemistry into novel molecular entities.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential drug candidates targeting neurological and metabolic disorders.
• Asymmetric Synthesis: Used in catalytic and stoichiometric asymmetric reactions to construct complex molecules with high enantiomeric excess.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: An intermediate in the research of novel, enantiopure pesticides and herbicides.
• Reference Standard: Employed as an analytical standard for method development and quality control in chiral analysis (e.g., HPLC, SFC).
• Process Chemistry: Scaled for use in route development and optimization for the commercial manufacturing of chiral APIs.

Basic Information

Product Name	(S)-Methyl-3-(1-Methyl-1H-Indol-3-Yl)-Phenyl-Propionate
CAS No.	429689-17-8
Molecular Formula	C20H21NO2
Molecular Weight	307.39 g/mol
Synonyms	(S)-Methyl 3-(1-Methyl-1H-indol-3-yl)-3-phenylpropanoate; Methyl (3S)-3-(1-Methylindol-3-yl)-3-phenylpropanoate; (S)-3-(1-Methyl-1H-indol-3-yl)-3-phenylpropionic acid methyl ester; (S)-Methyl 3-(1-methylindol-3-yl)-3-phenylpropionate; (S)-3-(1-Methyl-1H-indol-3-yl)-3-phenylpropanoic acid methyl ester; (S)-1-Methyl-3-(3-methoxy-3-oxo-1-phenylpropyl)-1H-indole
EINECS	Contact for details

Quality Control

Our (S)-Methyl-3-(1-Methyl-1H-Indol-3-Yl)-Phenyl-Propionate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.