Description

trans-3-Azido-1-Boc-4-Methoxypyrrolidine is a high-purity, multi-functional pyrrolidine derivative designed for advanced synthetic chemistry. This compound serves as a critical building block in the synthesis of complex molecules, offering a reactive azide group and a protected amine for selective transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for introducing nitrogen-rich heterocycles.
• Click Chemistry Reagent: Utilized in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation, polymer modification, and material science applications.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with specific biological activity.
• Peptidomimetic Research: Used to create conformationally constrained peptide analogs and protease inhibitors.
• Ligand and Catalyst Development: Serves as a scaffold for creating novel chiral ligands and organocatalysts for asymmetric synthesis.
• Academic and R&D Laboratories: Employed in methodological studies and the exploration of new synthetic pathways.

Basic Information

Product Name	trans-3-Azido-1-Boc-4-Methoxypyrrolidine
CAS No.	429673-78-9
Molecular Formula	C11H20N4O3
Molecular Weight	256.30 g/mol
Synonyms	1-Boc-3-azido-4-methoxypyrrolidine; tert-Butyl 3-azido-4-methoxypyrrolidine-1-carboxylate; 3-Azido-1-(tert-butoxycarbonyl)-4-methoxypyrrolidine; 1-N-Boc-3-azido-4-methoxypyrrolidine; (3R,4R)-1-(tert-Butoxycarbonyl)-3-azido-4-methoxypyrrolidine (trans isomer); (3S,4S)-1-(tert-Butoxycarbonyl)-3-azido-4-methoxypyrrolidine (trans isomer); Azido-Boc-methoxypyrrolidine; Pyrrolidine, 3-azido-1-[(1,1-dimethylethoxy)carbonyl]-4-methoxy-, trans-
EINECS	Contact for details

Quality Control

Our trans-3-Azido-1-Boc-4-Methoxypyrrolidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications in cGMP-compliant research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C (refrigerated) or as specified on the label. This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.