Description

Benzene, 2,4-Difluoro-1-Isocyano- (9Ci) is a specialized aromatic building block featuring both fluorine and isocyanide functional groups, making it a valuable synthon for advanced organic synthesis. Its unique structure provides a versatile handle for constructing complex molecules, particularly in the development of pharmaceuticals and agrochemicals. This high-purity intermediate is essential for research and development chemists and process scale-up teams in the fine chemical and life science industries. The compound is supplied under strict quality control to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the difluoro and isocyano groups impart specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of novel polymers and functional materials with tailored electronic or surface properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems due to the reactivity of the isocyanide group.

Basic Information

Product Name	Benzene, 2,4-Difluoro-1-Isocyano- (9Ci)
CAS No.	428818-83-1
Molecular Formula	C7H3F2N
Molecular Weight	139.11 g/mol
Synonyms	1-Isocyano-2,4-difluorobenzene; 2,4-Difluorophenyl isocyanide; 2,4-Difluorobenzene isonitrile; 2,4-Difluorophenyl isonitrile; (2,4-Difluorophenyl)isocyanide; NSC 405124; 2,4-Difluoro-1-isocyanobenzene
EINECS	Contact for details

Quality Control

Our Benzene, 2,4-Difluoro-1-Isocyano- (9Ci) is manufactured under a strict quality management system. Each batch is analyzed to ensure it meets high-purity standards suitable for research and industrial synthesis. Comprehensive testing includes identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.