Description

3-Pyrrolidinecarboxylicacid,5-Oxo-,Methylester,(3S)-(9Ci) is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. This compound, with CAS number 428518-31-4, is valued for its rigid pyrrolidinone scaffold and ester functionality, which are critical for constructing complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of protease inhibitors, neurological agents, and other bioactive molecules.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging its heterocyclic structure.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands used in asymmetric catalysis.
• Peptidomimetics: The 5-oxopyrrolidine-3-carboxylate core is a valuable scaffold for designing peptide mimics.
• Academic & R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs for client-specific projects.

Basic Information

Product Name	3-Pyrrolidinecarboxylicacid,5-Oxo-,Methylester,(3S)-(9Ci)
CAS No.	428518-31-4
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	(3S)-5-Oxo-1-pyrrolidine-3-carboxylic acid methyl ester; Methyl (3S)-5-oxopyrrolidine-3-carboxylate; (S)-Methyl 5-oxopyrrolidine-3-carboxylate; L-Pyroglutamic acid methyl ester; Methyl (S)-(-)-5-oxo-2-pyrrolidinecarboxylate; (S)-(-)-5-Oxo-2-pyrrolidinecarboxylic acid methyl ester; (3S)-5-Oxopyrrolidine-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 3-Pyrrolidinecarboxylicacid,5-Oxo-,Methylester,(3S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.