Description

(R)-2-tert-Butoxycarbonylamino-Succinic Acid Bis(Diethyl Ester) is a high-purity chiral building block and protected amino acid derivative essential for advanced organic synthesis. This compound matters for its role in constructing complex peptide mimetics and active pharmaceutical ingredients (APIs) with precise stereochemistry. It is critically needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries for developing novel therapeutics and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of peptide-based drugs and protease inhibitors.
• Peptidomimetic Research: Building block for creating non-natural amino acids and constrained peptides in drug discovery.
• Asymmetric Synthesis: Used in stereoselective reactions to introduce the (R)-configured aspartic acid derivative into target molecules.
• API Development: Intermediate in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Bioconjugation Chemistry: Serves as a protected linker or spacer molecule for bioconjugation applications.
• Fine Chemical Production: Employed in the manufacture of specialty catalysts and chiral auxiliaries.

Basic Information

Product Name	(R)-2-tert-Butoxycarbonylamino-Succinic Acid Bis(Diethyl Ester)
CAS No.	428440-11-3
Molecular Formula	C17H31NO7
Molecular Weight	361.43 g/mol
Synonyms	(R)-Boc-Asp(OEt)-OEt; (R)-2-((tert-Butoxycarbonyl)amino)butanedioic acid 1,4-diethyl ester; Diethyl (R)-2-[(tert-butoxycarbonyl)amino]succinate; (R)-Boc-Aspartic acid diethyl ester; (R)-Boc-Asp(OEt)2; (R)-N-Boc-Aspartic acid diethyl ester; (R)-2-(Boc-amino)succinic acid diethyl ester; (2R)-2-[[(2-Methylpropan-2-yl)oxycarbonyl]amino]butanedioic acid diethyl ester
EINECS	Contact for details

Quality Control

Our (R)-2-tert-Butoxycarbonylamino-Succinic Acid Bis(Diethyl Ester) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and cGMP-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.