Description

(2-(3,4,5-Trimethoxyphenyl)Pyridin-4-Yl)Methanamine is a high-purity organic building block featuring a pyridine core linked to a trimethoxyphenyl moiety via a methylamine bridge. This compound is valued for its role as a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is essential for medicinal chemists and process development scientists working in drug discovery, especially for targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Chemical Biology Probe Development: Serves as a core scaffold for developing tool compounds to study biological mechanisms and protein interactions.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale manufacturing of advanced drug candidates.
• Academic Research: Utilized in universities and research institutes for synthetic organic chemistry projects and the development of new methodologies.
• Custom Synthesis & Contract Manufacturing: A starting material for the bespoke production of specialized fine chemicals and advanced intermediates.

Basic Information

Product Name	(2-(3,4,5-Trimethoxyphenyl)Pyridin-4-Yl)Methanamine
CAS No.	427885-87-8
Molecular Formula	C15H18N2O3
Molecular Weight	274.32 g/mol
Synonyms	4-(Aminomethyl)-2-(3,4,5-trimethoxyphenyl)pyridine; 1-(3,4,5-Trimethoxyphenyl)-4-(aminomethyl)pyridine; (2-(3,4,5-Trimethoxyphenyl)-4-pyridinyl)methanamine; 4-Pyridinemethanamine, 2-(3,4,5-trimethoxyphenyl)-; 2-(3,4,5-Trimethoxyphenyl)-4-pyridinemethanamine; 4-(Aminomethyl)-2-(3,4,5-trimethoxyphenyl)pyridine; CAS 427885-87-8
EINECS	Contact for details

Quality Control

Our (2-(3,4,5-Trimethoxyphenyl)Pyridin-4-Yl)Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.