Description

4-(Chloromethyl)-2-(3,4,5-Trimethoxyphenyl)Pyridine is a high-purity, multi-functional chemical intermediate with a distinct pyridine core substituted with chloromethyl and trimethoxyphenyl groups. This compound is valued for its versatile reactivity, where the chloromethyl moiety serves as a key handle for further synthetic elaboration, making it a critical building block in advanced organic synthesis. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and complex specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its unique heterocyclic structure.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science: Employed in the research and development of advanced organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and diagnostic agents in biochemical research.

Basic Information

Product Name	4-(Chloromethyl)-2-(3,4,5-Trimethoxyphenyl)Pyridine
CAS No.	427885-85-6
Molecular Formula	C16H16ClNO3
Molecular Weight	305.76 g/mol
Synonyms	2-(3,4,5-Trimethoxyphenyl)-4-(chloromethyl)pyridine; 4-(Chloromethyl)-2-(3,4,5-trimethoxyphenyl)pyridine; 2-(3,4,5-Trimethoxyphenyl)-4-pyridinemethanol, chloromethyl ether; 427885-85-6; 4-(Chloromethyl)-2-(3,4,5-trimethoxy-phenyl)pyridine; 4-(Chloromethyl)-2-(3,4,5-trimethoxyphenyl)pyridine (CAS 427885-85-6)
EINECS	Contact for details

Quality Control

Our 4-(Chloromethyl)-2-(3,4,5-Trimethoxyphenyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.