Description

Ethyl 2-(3,4,5-Trimethoxyphenyl)pyridine-4-carboxylate is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it serves as a critical intermediate for constructing complex molecules with potential biological activity, offering a unique scaffold for medicinal chemistry research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise chemical to develop new active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting kinase inhibition and other enzyme-related pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Employed in the development of molecular probes to study enzyme function and cellular signaling pathways.
• Fine Chemical Synthesis: Serves as a building block for creating complex, high-value specialty chemicals and advanced materials.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) settings for exploratory synthetic chemistry and method development.

Basic Information

Product Name	Ethyl 2-(3,4,5-Trimethoxyphenyl)pyridine-4-carboxylate
CAS No.	427885-83-4
Molecular Formula	C17H19NO5
Molecular Weight	317.34 g/mol
Synonyms	Ethyl 2-(3,4,5-trimethoxyphenyl)-4-pyridinecarboxylate; 4-Pyridinecarboxylic acid, 2-(3,4,5-trimethoxyphenyl)-, ethyl ester; 2-(3,4,5-Trimethoxyphenyl)isonicotinic acid ethyl ester; Ethyl 2-(3,4,5-trimethoxyphenyl)isonicotinate; 427885-83-4; 2-(3,4,5-Trimethoxyphenyl)-4-(ethoxycarbonyl)pyridine
EINECS	Contact for details

Quality Control

Our Ethyl 2-(3,4,5-Trimethoxyphenyl)pyridine-4-carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supported by a detailed Certificate of Analysis (COA). We are committed to meeting the stringent requirements of research and development, with specifications tailored for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.