Description

6'-Chloro-2,3,5,6-Tetrahydro-[1,2']Bipyrazinyl-4-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate of significant importance in modern drug discovery and development. This compound serves as a critical building block for the synthesis of complex heterocyclic molecules, enabling the creation of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on developing new active pharmaceutical ingredients (APIs), particularly in areas requiring sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially for central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to explore novel chemical space and improve drug-like properties.
• API Synthesis: Serves as a crucial building block in the multi-step synthesis of complex target molecules for pre-clinical and clinical studies.
• Chemical Biology Probes: Employed in the development of specialized chemical tools and probes for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the pharmaceutical industry.

Basic Information

Product Name	6'-Chloro-2,3,5,6-Tetrahydro-[1,2']Bipyrazinyl-4-Carboxylic Acid tert-Butyl Ester
CAS No.	426829-52-9
Molecular Formula	C14H21ClN4O2
Molecular Weight	312.80 g/mol
Synonyms	tert-Butyl 6'-chloro-3,4,5,6-tetrahydro-2H-[1,2'-bipyrazine]-4-carboxylate; 6'-Chloro-3,4,5,6-tetrahydro-2H-[1,2'-bipyrazine]-4-carboxylic acid 1,1-dimethylethyl ester; 6'-Chloro-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-carboxylic acid tert-butyl ester; 6'-Chloro-2,3,5,6-tetrahydro[1,2']bipyrazinyl-4-carboxylic acid tert-butyl ester; 6'-Chloro-2,3,5,6-tetrahydro[1,2']bipyrazinyl-4-carboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 6'-Chloro-2,3,5,6-Tetrahydro-[1,2']Bipyrazinyl-4-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.