Description

1-tert-Butyl 2-Ethyl 1H-Indole-1,2-Dicarboxylate is a high-purity, synthetically valuable indole derivative used as a key protected intermediate in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular building blocks for the development of complex heterocyclic systems. It is primarily utilized in pharmaceutical R&D for the synthesis of novel active pharmaceutical ingredients (APIs) and in agrochemical research for creating new crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of complex indole-based drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in research and development for creating novel herbicides, fungicides, and insecticides with indole core structures.
• Organic Synthesis Reagent: Serves as a protected carboxylate intermediate in complex organic transformations, including palladium-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic semiconductors, dyes, and photoresponsive materials due to the indole scaffold's electronic properties.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting methodological studies in heterocyclic chemistry.

Basic Information

Product Name	1-tert-Butyl 2-Ethyl 1H-Indole-1,2-Dicarboxylate
CAS No.	426826-79-1
Molecular Formula	C17H21NO4
Molecular Weight	303.35 g/mol
Synonyms	1H-Indole-1,2-dicarboxylic acid, 1-(1,1-dimethylethyl) 2-ethyl ester; 1-tert-Butoxycarbonyl-2-ethoxycarbonylindole; 1-Boc-2-Ethoxycarbonylindole; 1-(tert-Butyl) 2-ethyl indole-1,2-dicarboxylate; Indole-1,2-dicarboxylic Acid 1-tert-Butyl 2-Ethyl Ester; 2-Ethoxycarbonyl-1-Boc-indole; 426826-79-1; tert-Butyl 2-ethoxy-1H-indole-1,2-dicarboxylate
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 2-Ethyl 1H-Indole-1,2-Dicarboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) guidelines where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.