Description

2-Chloro-5-Iodo-Pyridin-3-Ylamine is a halogenated pyridine derivative that serves as a versatile and high-value building block in advanced organic synthesis. Its unique structure, featuring both chloro and iodo substituents on the pyridine ring, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides due to its halogenated heterocyclic core.
• Material Science: Serves as a precursor for ligands in catalysis and for creating functionalized polymers or organic electronic materials.
• Chemical Research: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic aromatic substitution to introduce complex functionalities.
• Ligand Preparation: Useful for synthesizing novel chelating agents and ligands for metal-organic frameworks (MOFs) or coordination chemistry.

Basic Information

Product Name	2-Chloro-5-Iodo-Pyridin-3-Ylamine
CAS No.	426463-09-4
Molecular Formula	C5H4ClIN2
Molecular Weight	254.45 g/mol
Synonyms	3-Amino-2-chloro-5-iodopyridine; 2-Chloro-5-iodopyridin-3-amine; 5-Iodo-2-chloropyridin-3-amine; 2-Chloro-5-iodo-3-pyridinamine; 3-Pyridinamine, 2-chloro-5-iodo-; 2-Chloro-5-iodo-3-aminopyridine; 2-Chloro-5-iodo-3-pyridylamine
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Iodo-Pyridin-3-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.