Description

1-(4-Chlorophenyl)-2,2,2-Trifluoroethyl Hydrogen Phenylphosphonate is a specialized organophosphorus compound that serves as a critical intermediate in advanced chemical synthesis. Its unique structure, featuring both phosphonate and trifluoroethyl-chlorophenyl groups, makes it a valuable building block for creating molecules with tailored properties. This high-purity intermediate is primarily sought by research institutions and manufacturers in the agrochemical and pharmaceutical sectors for developing novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: Key precursor in the synthesis of novel insecticides, herbicides, and fungicides, leveraging the bioactivity of the phosphonate moiety.
• Pharmaceutical Research: Used as a building block in medicinal chemistry for developing potential drug candidates, especially protease inhibitors or enzyme modulators.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized phosphonate-based ligands used in asymmetric catalysis and metal complexation.
• Material Science: Intermediate for synthesizing flame retardants, plasticizers, or specialty polymers where phosphorus and fluorine incorporation is desired.
• Chemical Biology Probes: Utilized in the development of activity-based probes and molecular tools for studying biochemical pathways.

Basic Information

Product Name	1-(4-Chlorophenyl)-2,2,2-Trifluoroethyl Hydrogen Phenylphosphonate
CAS No.	426214-58-6
Molecular Formula	C14H11ClF3O3P
Molecular Weight	350.65 g/mol
Synonyms	Hydrogen Phenylphosphonic Acid 1-(4-Chlorophenyl)-2,2,2-Trifluoroethyl Ester; Phenylphosphonic Acid 2,2,2-Trifluoro-1-(4-chlorophenyl)ethyl Ester; 1-(p-Chlorophenyl)-2,2,2-trifluoroethyl Phenylphosphonate; (4-Chlorophenyl)(trifluoromethyl)methyl Phenylphosphonate; α-(4-Chlorophenyl)-α-(trifluoromethyl)methyl Phenylphosphonate; Phosphonic Acid, P-, 1-(4-Chlorophenyl)-2,2,2-trifluoroethyl Ester
EINECS	Contact for details

Quality Control

Our production of 1-(4-Chlorophenyl)-2,2,2-Trifluoroethyl Hydrogen Phenylphosphonate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider using an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.