Description

[(4-Ethoxy-Phenyl)-(Toluene-4-Sulfonyl)-Amino]-Acetic Acid Methyl Ester is a high-purity, specialized organic intermediate of significant value in advanced chemical synthesis. This compound matters for its role as a key building block in the development of complex molecules, offering a unique sulfonamide-protected amino acid ester functionality. Pharmaceutical R&D laboratories and fine chemical manufacturers need it for the synthesis of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel drug candidates, particularly those requiring sulfonamide or protected amino acid motifs.
• Peptidomimetic Research: Used in medicinal chemistry for the design and synthesis of peptide analogs and enzyme inhibitors.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides or fungicides with tailored biological activity.
• Material Science: Potential monomer or additive in the synthesis of specialized polymers with specific functional properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploratory organic synthesis projects.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client-specific applications.

Basic Information

Product Name	[(4-Ethoxy-Phenyl)-(Toluene-4-Sulfonyl)-Amino]-Acetic Acid Methyl Ester
CAS No.	425427-30-1
Molecular Formula	C18H21NO5S
Molecular Weight	363.43 g/mol
Synonyms	Methyl [(4-ethoxyphenyl)(4-methylphenyl)sulfonylamino]acetate; Methyl 2-[(4-ethoxyphenyl)(tosyl)amino]acetate; N-[(4-Ethoxyphenyl)(4-methylphenyl)sulfonyl]glycine Methyl Ester; Methyl N-(4-ethoxyphenyl)-N-(p-tolylsulfonyl)glycinate; Tosyl-4-ethoxyaniline Glycine Methyl Ester; p-Toluenesulfonamide Derivative; Glycine, N-[(4-ethoxyphenyl)(4-methylphenyl)sulfonyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our production of [(4-Ethoxy-Phenyl)-(Toluene-4-Sulfonyl)-Amino]-Acetic Acid Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods (IR, NMR) and purity assessment by HPLC. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.