Description

4'-Methoxy-1'H-Spiro[Cyclopropane-1,3'-Indole]-2'-One is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic indole scaffold. This compound is of significant value for research and development in medicinal chemistry, particularly for its potential role in modulating biological pathways. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its spirocyclic and indole-based architecture.
• Biochemical Tool Compound: Serves as a probe or reference standard in biochemical assays to study specific enzyme or receptor interactions.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to construct complex heterocyclic frameworks for agrochemical or material science applications.
• Contract Research & Manufacturing (CRAM): Supplied to organizations offering custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	4'-Methoxy-1'H-Spiro[Cyclopropane-1,3'-Indole]-2'-One
CAS No.	424792-50-7
Molecular Formula	C12H11NO2
Molecular Weight	201.22 g/mol
Synonyms	4'-Methoxy-1'H-spiro[cyclopropane-1,3'-indol]-2'(1'H)-one; 1'H-Spiro[cyclopropane-1,3'-indole]-2'-one, 4'-methoxy-; 4-Methoxyspiro[cyclopropane-1,3'-indolin]-2'-one; Spiro[cyclopropane-1,3'-indole]-2'-one, 4'-methoxy-; 424792-50-7
EINECS	Contact for details

Quality Control

Our 4'-Methoxy-1'H-Spiro[Cyclopropane-1,3'-Indole]-2'-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided and can be tailored to meet specific client requirements or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.