Description

1,4,5,6-Tetrahydro-2-Methyl-4-(3-Nitrophenyl)-6-Oxo-3-Pyridinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development pipelines. It is essential for pharmaceutical manufacturers and R&D organizations focused on developing new therapeutic agents in specialized chemical spaces.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold for constructing final API molecules requiring the tetrahydro-6-oxo-pyridinecarboxylate moiety.
• Contract Manufacturing (CMO/CDMO): Supplied to contract research and manufacturing organizations for custom synthesis projects and scale-up activities.
• Chemical Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	1,4,5,6-Tetrahydro-2-Methyl-4-(3-Nitrophenyl)-6-Oxo-3-Pyridinecarboxylic Acid
CAS No.	423120-04-1
Molecular Formula	C14H14N2O5
Molecular Weight	290.27 g/mol
Synonyms	4-(3-Nitrophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxylic acid; 2-Methyl-4-(3-nitrophenyl)-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxylic acid; 3-Pyridinecarboxylic acid, 1,4,5,6-tetrahydro-2-methyl-4-(3-nitrophenyl)-6-oxo-; CAS 423120-04-1
EINECS	Contact for details

Quality Control

Our 1,4,5,6-Tetrahydro-2-Methyl-4-(3-Nitrophenyl)-6-Oxo-3-Pyridinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.