Description

3-Bromo-5-(Tetrahydro-2H-Pyran-4-Yloxy)Pyridine is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound is valued for its unique pyridine core functionalized with both a bromo substituent and a tetrahydropyranyloxy group, enabling precise molecular construction. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of potential new drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers.
• Chemical Biology Probes: Useful for creating molecular probes to study biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, multi-step organic transformations.

Basic Information

Product Name	3-Bromo-5-(Tetrahydro-2H-Pyran-4-Yloxy)Pyridine
CAS No.	422557-23-1
Molecular Formula	C10H12BrNO2
Molecular Weight	258.11 g/mol
Synonyms	3-Bromo-5-[(oxan-4-yl)oxy]pyridine; 3-Bromo-5-(tetrahydropyran-4-yloxy)pyridine; 5-Bromo-3-(tetrahydro-2H-pyran-4-yloxy)pyridine; Pyridine, 3-bromo-5-(tetrahydro-2H-pyran-4-yloxy)-; THP-protected 5-bromo-3-hydroxypyridine derivative; 422557-23-1
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(Tetrahydro-2H-Pyran-4-Yloxy)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP standards where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.