Description

Ethyl 6-Methyl-2-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its imidazopyridine core and trifluoromethyl group. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), offering significant value in medicinal chemistry for its role in modulating drug-like properties. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas such as central nervous system (CNS) and anti-infective drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its imidazopyridine scaffold and fluorine substitution.
• API Development: Serves as a critical precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Agrochemical Research: Potential application in the development of new agrochemicals, leveraging the biological activity of the imidazopyridine heterocycle.

Basic Information

Product Name	Ethyl 6-Methyl-2-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-3-Carboxylate
CAS No.	420130-61-6
Molecular Formula	C12H11F3N2O2
Molecular Weight	272.23 g/mol
Synonyms	Ethyl 6-methyl-2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate; 6-Methyl-2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester; Imidazo[1,2-a]pyridine-3-carboxylic acid, 6-methyl-2-(trifluoromethyl)-, ethyl ester; Ethyl 2-(trifluoromethyl)-6-methylimidazo[1,2-a]pyridine-3-carboxylate; CAS 420130-61-6
EINECS	Contact for details

Quality Control

Our Ethyl 6-Methyl-2-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.