Description

1H-Pyrrolo[2,3-B]Pyridine, 1-[(4-Fluorophenyl)Methyl]- is a high-purity, advanced pharmaceutical intermediate with the CAS number 418795-10-5. This heterocyclic compound is a critical building block in modern medicinal chemistry, valued for its unique fused-ring structure that serves as a core scaffold for bioactive molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, especially kinase inhibitors.
• Medicinal Chemistry Research: Serves as a privileged scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Oncology Drug Development: Used in the research and production of potential anti-cancer agents due to its structural similarity to known bioactive motifs.
• CNS-Active Compound Synthesis: Employed in creating novel candidates for treating neurological disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and drug design methodologies.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 1-[(4-Fluorophenyl)Methyl]-
CAS No.	418795-10-5
Molecular Formula	C14H11FN2
Molecular Weight	226.25 g/mol
Synonyms	1-[(4-Fluorophenyl)methyl]-1H-pyrrolo[2,3-b]pyridine; 1-(4-Fluorobenzyl)-1H-pyrrolo[2,3-b]pyridine; 1-(4-Fluorobenzyl)-7-azaindole; 7-Azaindole, 1-(4-fluorobenzyl)-; 1H-Pyrrolo[2,3-b]pyridine, 1-[(4-fluorophenyl)methyl]-; 418795-10-5; 1-(4-Fluorobenzyl)-1H-pyrrolo[2,3-b]pyridine; 1-(p-Fluorobenzyl)-7-azaindole
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 1-[(4-Fluorophenyl)Methyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring consistency and traceability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.