Description

(S)-n-Boc-1,2,3,6-Tetrahydro-2-Picolinic Acid is a high-purity chiral building block and key pharmaceutical intermediate. This compound matters for its critical role in the synthesis of complex molecules, particularly in medicinal chemistry and asymmetric synthesis. Pharmaceutical R&D laboratories and fine chemical manufacturers need it for developing active pharmaceutical ingredients (APIs), especially those targeting neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a building block for constructing complex molecules with high enantiomeric purity in medicinal chemistry.
• Protease Inhibitor Research: Serves as a precursor in the development of protease inhibitors and other enzyme-targeted therapeutics.
• Peptidomimetics: Integral for creating peptidomimetic scaffolds used in drug discovery programs.
• Ligand Synthesis: Employed in the preparation of chiral ligands for catalysis and asymmetric transformations.
• Academic & Contract Research: Utilized in university and CRO settings for exploratory research in organic and medicinal chemistry.

Basic Information

Product Name	(S)-n-Boc-1,2,3,6-Tetrahydro-2-Picolinic Acid
CAS No.	417726-36-4
Molecular Formula	C11H17NO4
Molecular Weight	227.26 g/mol
Synonyms	(S)-1-(tert-Butoxycarbonyl)-1,2,3,6-tetrahydro-2-picolinic acid; (S)-1-Boc-1,2,3,6-tetrahydropyridine-2-carboxylic acid; (S)-2-Picolinic acid, 1,2,3,6-tetrahydro-1-[(1,1-dimethylethoxy)carbonyl]-; (S)-N-Boc-1,2,3,6-tetrahydro-2-pyridinecarboxylic acid; (S)-1-Boc-1,2,3,6-tetrahydro-2-pyridinecarboxylic acid; (S)-N-Boc-1,2,3,6-tetrahydro-2-picolinic acid; (S)-1,2,3,6-Tetrahydro-1-[(1,1-dimethylethoxy)carbonyl]-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) and spectroscopic confirmation are available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.