Description

4-Chloro-3-Iodo-Pyridin-2-Ylamine is a halogenated pyridine derivative that serves as a versatile and high-value synthetic building block in advanced organic chemistry. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules with tailored biological and physical properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and pesticides with specific modes of action.
• Ligand and Catalyst Development: Used to create specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Intermediate in the production of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes and tags used in biochemical assays and imaging.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	4-Chloro-3-Iodo-Pyridin-2-Ylamine
CAS No.	417721-69-8
Molecular Formula	C5H4ClIN2
Molecular Weight	254.46 g/mol
Synonyms	2-Amino-4-chloro-3-iodopyridine; 4-Chloro-3-iodopyridin-2-amine; 3-Iodo-4-chloropyridin-2-amine; 4-Chloro-3-iodo-2-pyridinamine; 2-Pyridinamine, 4-chloro-3-iodo-; 4-Chloro-3-iodo-2-aminopyridine; 4-Chloro-3-iodo-2-pyridylamine
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-3-Iodo-Pyridin-2-Ylamine is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) including purity (HPLC), identity confirmation (NMR, IR), and impurity profile is supplied with each shipment. Our quality protocols are designed to support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.