Description

2-(5-Nitropyridin-2-Yl)-1,2,3,4-Tetrahydroisoquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel therapeutic and crop protection agents.

Application

• Critical pharmaceutical intermediate for the synthesis of drug candidates targeting central nervous system (CNS) disorders.
• Key precursor in the research and development of kinase inhibitors and other small-molecule therapeutics.
• Building block for agrochemical active ingredients, particularly in the development of new herbicides and insecticides.
• Versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Used in academic and industrial R&D for exploring novel heterocyclic chemistry and reaction pathways.
• Intermediate for the production of dyes and pigments with specialized optical properties.

Basic Information

Product Name	2-(5-Nitropyridin-2-Yl)-1,2,3,4-Tetrahydroisoquinoline
CAS No.	416885-42-2
Molecular Formula	C₁₄H₁₃N₃O₂
Molecular Weight	255.27 g/mol
Synonyms	2-(5-Nitro-2-pyridinyl)-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-2-(5-nitro-2-pyridinyl)isoquinoline; 5-Nitro-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)pyridine; 416885-42-2; 2-(5-Nitropyridin-2-yl)-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Every batch of 2-(5-Nitropyridin-2-Yl)-1,2,3,4-Tetrahydroisoquinoline is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.