Description

4-Pyridinepropanoicacid,-α--Hydroxy-,(-α-R)-(9Ci) is a high-purity chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of optically active pharmaceuticals and complex molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for applications requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides where specific stereochemistry enhances efficacy and reduces environmental impact.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Biochemical Research: Employed in the study of enzyme mechanisms and as a standard or reagent in analytical method development for chiral separations.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.

Basic Information

Product Name	4-Pyridinepropanoicacid,-α--Hydroxy-,(-α-R)-(9Ci)
CAS No.	413627-03-9
Molecular Formula	C8H9NO3
Molecular Weight	167.16 g/mol
Synonyms	(R)-2-Hydroxy-3-(4-pyridyl)propanoic acid; (αR)-α-Hydroxy-4-pyridinepropanoic acid; (R)-2-Hydroxy-3-(pyridin-4-yl)propanoic acid; 4-Pyridinepropanoic acid, α-hydroxy-, (αR)-; (R)-HPPA; (R)-3-(4-Pyridyl)lactic acid; (R)-4-Pyridyl lactic acid; (R)-HPLA
EINECS	Contact for details

Quality Control

Our 4-Pyridinepropanoicacid,-α--Hydroxy-,(-α-R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.